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JLee's Laboratory

Vascular Biology and Visual Science

Department of Ophthalmology

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Asan Institute for

Life Science

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Translational Biomedical Research 

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Korean Society for Vascular Biology and Medicine

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What We Do

We are mainly focusing on the structure and function of blood vessels for the maintenance of the central nervous system, including the retina and brain.

Our laboratory is performing multidisciplinary research in molecular biology, biochemistry,  bioimaging, translational research, and drug development.

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Research Topics

Endothelial-Pericyte Interactions

Dissect the mechanisms of dynamic changes of perivascular cells in the normal and several diseases.

Normalization and restoration of blood vessels

Discover the pathogenic factors associated with endothelial-pericyte interactions, and normalize the ultrastructure of CNS vasculature.

Ultrastructures of Fenestrated Capillaries in CNS

Regulation of endothelial fenestration and molecular transport through the windows of blood vessels.

Drug development

Next-generation treatments for neurovascular diseases, including diabetic retinopathy, age-related macular degeneration, and Alzheimer's disease.

Lab Gallery

Gallery 

Our Collaborators

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